Monthly Archives: July 2024

How to build a PK-PD model?

Hello fellow coffee and cat lovers, as with the first caffeine simulator, I will be going through how to run PK-PD simulations too. Link to coffee simulator 2: https://lnkd.in/dAiS3igB We have previously covered how to run PK simulations which you … Continue reading

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Why do pharmacokinetic-pharmacodynamic (PK-PD) modeling?

It takes 2 hands to clap. Previously, in my first coffee simulator,  https://janicegoh.shinyapps.io/CoffeeSimulator/ we used a simple threshold to determine caffeine efficacy and toxicity. However, this efficacy alone does not tell us exactly how alert we will be with a … Continue reading

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