Monthly Archives: February 2025
Neural ODEs vs ODEs – what’s the difference?
Part 4 of ScienceJournalJourneys – Hi I am your SG pharmacometrician, an early career researcher here to share my expertise and learnings about everything pharmacometrics. For any PK/PD modeler, ODEs are a staple in our models that help us to … Continue reading
ScienceJournalJourney3 – the translation problem in drug development
Drug development often follows a series of experiments of exponentially increasing costs. After identifying a target and a few hits, novel drugs are then tested in large scale against in vitro assays e.g. bacterial kill in a 96 well plate, … Continue reading
ScienceJournalJourney2 – The one surprising use of Fexofenadine (Telfast)
To the average consumer, fexofenadine, or better known by its brand name, Telfast, is a non-sedating anti-allergy medication that can help to stop itches and runny noses. Fexofenadine is an over-the-counter medication that does not require frequent monitoring or dose … Continue reading
Infinity stoned – a pharmacometrician’s take on Thanos in Squid Game 2
Disclaimer: this is purely a tongue in cheek article for educational purposes. In no way do I condone the use of illegal drugs or encourage its use. Also, potential spoilers ahead. Since the season 2 release, Squid Game is once … Continue reading
Has AI taken over my job? A comparison of ChatGPT and DeepSeek for generating NONMEM scripts
Prompt: Develop a 1 compartment oral absorption PK model with linear elimination in NONMEM I did a direct comparison of the script outputs in the table below. For the sake of brevity, only CL was discussed in the $PK block, … Continue reading
Singapore Pharmacometrics 