Tag Archives: health

Export control in a digital world – is synthetic data the future for clinical studies?

Part 5 of ScienceJournalJourneys – Hi I am your SG pharmacometrician, an early career researcher here to share the latest trends and interesting facts in pharmacometrics When you bring goods to another country, it is normal for the goods to … Continue reading

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ScienceJournalJourney 1:  How do drug manufacturers make dosing recommendations?

Hi all, Happy New Year to everyone! I’m starting a new series this year called #ScienceJournalJourney where I review an interesting journal article and give a quick layman summary on it. As your favorite post doc influencer on LinkedIn, I … Continue reading

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How can pharmacometrics benefit clinical practice and vice versa?

Last weekend, I had the privilege of speaking about my work in pharmacogenomics at the Singapore Pharmacy Congress. It was a good time of getting to meet old friends and network with the new generation of pharmacists. Just as how … Continue reading

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How to build a PK-PD model?

Hello fellow coffee and cat lovers, as with the first caffeine simulator, I will be going through how to run PK-PD simulations too. Link to coffee simulator 2: https://lnkd.in/dAiS3igB We have previously covered how to run PK simulations which you … Continue reading

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Artificial sweetener choices – to absorb or not to absorb?

Artificial sweeteners are in the news again regarding potential new health risks. In particular, xylitol (a common artificial sugar) has been called into question as a prothrombotic (causing an increased risk of blood clots and thus stroke and heart attacks) … Continue reading

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How can our genes affect drug levels?

We all respond to drugs differently. As many of you have pointed out while using the coffee simulator https://janicegoh.shinyapps.io/CoffeeSimulator/ over the past few months, the profile shown there does not always accurately describe your experience with coffee. This is because … Continue reading

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Why does metformin cause a metallic taste in your mouth?

Hi all, life has been pretty busy lately, but I am still trying to post fun things I come across when I can. Hope you enjoy! A common but relatively harmless side effect of metformin is a lingering metallic taste … Continue reading

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Steamed fish

Today, I learnt to steam a whole fish.  It all started with me wandering around the Asian market. Whole tilapia was on sale, so I pointed at one and blankly nodded my head so the fish monger helped to clean … Continue reading

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What is the coffee simulator based on? (Part 2/5)

The main backbone of the coffee simulator comes from a pharmacokinetic model detailed in this paper by KY Seng et al. https://pubmed.ncbi.nlm.nih.gov/19125908/ Interestingly, there are a lot of papers related to caffeine out there for various purposes, such as defense … Continue reading

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