Tag Archives: Pharmacokinetics
Going beyond dose – why we need PK parameters
Good morning. In today’s weather report, we are expecting 1000L rain. – said no one ever. If I were to read the weather report before going to work, I intuitively want to know 3 things: the location the rain will … Continue reading
Scientific crystal balls – how pharmacometrics is like the weather forecast and why we need it
Hi all, I’m Janice, your SG pharmacometrician. To many of you, pharmacometrics, the study of modeling and simulation of drug levels and their outcomes, probably isn’t a term that comes easily to mind or something that you will regularly come … Continue reading
How can I use PK to help my research or clinical practice? (Part 5/5)
Thank you all for staying with me throughout this series! It has been fun sharing about my field with all of you! Over the past few weeks we have played with, and discussed the principles behind the coffee simulator, and … Continue reading
What about variability? (Part 4/5)
Let’s talk about variability. Many of you have correctly highlighted over the past few weeks that coffee absorption can be variable due to a variety of reasons. This not only occurs with coffee but with almost all drugs that we … Continue reading
What is the coffee simulator based on? (Part 2/5)
The main backbone of the coffee simulator comes from a pharmacokinetic model detailed in this paper by KY Seng et al. https://pubmed.ncbi.nlm.nih.gov/19125908/ Interestingly, there are a lot of papers related to caffeine out there for various purposes, such as defense … Continue reading
Optimizing your coffee dosage – why use modeling and simulation? (Part 1/5)
Hi all, here is a series I originally posted on linkedin as a soft introduction to the wonderful world of pharmacometrics. A lot of these posts revolve around a simple coffee simulator I built for the fun of optimizing your … Continue reading
Singapore Pharmacometrics 